An Update on Preventive Outlook for Supplementation of Vitamin-D against SARS-CoV-2 Infection

Abstract

The pandemic COVID-19 has a high death rate, which threatens nearly most of the world's population. The main reason for mortality in severe acute respiratory syndrome is intensified inflammatory activity followed by oxidative stress and inflammatory reactions on the lungs. To date, this pathology does not have a clear and conclusive cure troubling the world population, particularly elderly adults who are the major risk groups. In this sense, assessing the effectiveness of current pharmacological agents, which can be used to resolve or attenuate this pulmonary complication's seriousness that has threatened the lives of so many people globally, is of particular importance. In contrast to quarantine, public health interventions are urgently needed, reducing the risk of illness and death. Evidence reveals that vitamin D supplementation may be possible in treating COVID-19. Additionally, numerous trials and studies started to study the effect of vitamin D supplementation on patients with SARS-CoV-2 infection.